Cohort Studymoderate evidence
Low-carbohydrate and low-fat diets, genetic susceptibility, and long-term risk of dementia: a prospective cohort study.
The American journal of clinical nutrition·August 20, 2026·PMID 42567320
Why it mattersDietary patterns are modifiable risk factors for dementia, yet evidence on macronutrient composition and quality remains limited. This study suggests that the source and quality of macronutrients in low-carbohydrate diets matter for cognitive health, with plant-based and healthier choices potentially reducing dementia risk regardless of genetic predisposition.

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