Basic Sciencemoderate evidence
Mitochondria-lysosome coupling contributes to lysosome acidification and aging.
Molecular cell·June 18, 2026·PMID 42214330
Why it mattersLysosomal dysfunction is a hallmark of aging and many age-related diseases. This paper identifies a novel mechanism for lysosomal acidification that depends on mitochondrial proximity, offering a new target for interventions aimed at preserving cellular health during aging.
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