Randomized Trialhigh evidence
Physiological effects of trans-nasal humidified rapid insufflation ventilatory exchange (THRIVE) on lung volume dynamics during controlled apnea in patients with obesity: a randomized controlled trial.
Journal of clinical anesthesia·July 25, 2026·PMID 42501528
Why it mattersObese patients desaturate rapidly during apnea due to reduced functional residual capacity and atelectasis. Understanding how THRIVE attenuates lung volume decline provides physiological rationale for its use in prolonging safe apnea time, which is critical for airway management in this high-risk population.
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