Randomized Trialmoderate evidence
Calorie-Restricted DASH, Carbohydrate-Restricted, and Low-Purine Diets for Weight Loss and Urate Control in Men With Overweight or Obesity and Hyperuricemia: A Randomized Trial.
Diabetes care·September 15, 2026·PMID 42743064
Why it mattersFor patients with hyperuricemia and overweight, dietary weight loss is a cornerstone of management, but the optimal pattern is unclear. This trial shows that any of three structured calorie-restricted diets can achieve meaningful weight loss and modest urate lowering, with DASH offering better adherence and lean mass preservation.
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