Meta-Analysishigh evidence

Higher versus Routine Intraoperative Blood Pressure Targets in Noncardiac Surgery: A Systematic Review and Meta-analysis with Trial Sequential Analysis of Randomized Trials.

Anesthesiology·June 4, 2026·PMID 42241294

Why it matters

Intraoperative hypotension is common and linked to adverse outcomes, yet evidence on whether targeting higher pressures improves outcomes has been conflicting. This meta-analysis provides the most comprehensive randomized evidence to date, helping anesthesiologists avoid unnecessary aggressive blood pressure interventions that lack clear benefit for most major outcomes.

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