Randomized Trialhigh evidence
Aspirin in Patients with Chronic Coronary Syndrome Receiving Oral Anticoagulation.
The New England journal of medicine·October 23, 2025·PMID 40888725
Why it mattersThis trial provides high-quality evidence that adding aspirin to oral anticoagulation in stable coronary patients with prior stenting and high atherothrombotic risk is harmful, increasing both ischemic events and bleeding. It directly informs antithrombotic management in a common clinical scenario.
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