Cohort Studyhigh evidence
Joint non-linear dose-response associations of device-measured physical activity and cardiorespiratory fitness with cardiovascular disease: a cohort and Mendelian randomisation study.
British journal of sports medicine·May 28, 2026·PMID 42156172
Why it mattersIt quantifies how much MVPA is needed for meaningful CVD risk reduction beyond current guidelines and highlights the independent role of fitness, informing more precise exercise prescriptions for cardiovascular prevention.

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