Randomized Trialhigh evidence
Two-Year Retention of Benefits After Paired Vagus Nerve Stimulation in Stroke: Follow-Up of the VNS-REHAB Randomized Clinical Trial.
Neurology·August 11, 2026·PMID 42447422
Why it mattersSustained upper extremity recovery is a major challenge in chronic stroke. These 2-year data suggest that paired VNS can produce durable improvements in impairment, function, and participation, offering a meaningful long-term treatment option for selected patients with persistent arm/hand deficits.
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