Cohort Studyhigh evidence

Glucagon-like peptide-1 receptor agonists and risk of substance use disorders among US veterans with type 2 diabetes: cohort study.

BMJ (Clinical research ed.)·March 4, 2026·PMID 41781010

Why it matters

These findings suggest GLP-1 receptor agonists may have a broad preventive and therapeutic effect on substance use disorders, which are common and challenging in pain populations. This could influence medication selection in patients with comorbid diabetes and pain or addiction risk.

Infographic summary of Glucagon-like peptide-1 receptor agonists and risk of substance use disorders among US veterans with type 2 diabetes: cohort study.
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