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Plasma proteome profiling identified biomarkers for the differential diagnosis and molecular staging of neurodegenerative dementias.

Nature aging·July 20, 2026·PMID 42477094

Why it matters

Differential diagnosis of neurodegenerative dementias remains challenging, especially in early stages. A blood-based proteomic panel could provide a scalable, objective tool to distinguish Alzheimer's disease, Lewy body dementia, and frontotemporal dementia, potentially improving diagnostic accuracy and enabling earlier, more targeted management.

Infographic summary of Plasma proteome profiling identified biomarkers for the differential diagnosis and molecular staging of neurodegenerative dementias.
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