Meta-Analysishigh evidence

Effect of axial alignment on patient outcomes following total knee replacement (TKR): a systematic review and meta analysis.

The Knee·August 17, 2026·PMID 42607449

Why it matters

Post-operative dissatisfaction after TKR remains around 20%, and axial alignment is a modifiable factor that may influence outcomes. This synthesis provides quantitative evidence linking specific axial parameters to patient-reported improvements, informing surgical technique and alignment targets.

Infographic summary of Effect of axial alignment on patient outcomes following total knee replacement (TKR): a systematic review and meta analysis.
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