Randomized Trialhigh evidence

An integrated lifestyle intervention for mitigation of adverse effects associated with androgen deprivation therapy for prostate cancer (STAMINA): a multicentre, randomised trial.

The Lancet. Oncology·September 4, 2026·PMID 42697217

Why it matters

Androgen deprivation therapy causes significant quality-of-life and fatigue burdens, yet supervised exercise is rarely integrated into prostate cancer care. This trial provides robust evidence that a structured lifestyle program can be embedded in routine NHS practice and yields meaningful patient-centered benefits.

Infographic summary of An integrated lifestyle intervention for mitigation of adverse effects associated with androgen deprivation therapy for prostate cancer (STAMINA): a multicentre, randomised trial.
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