Meta-Analysismoderate evidence
Mortality Effect of Peripheral Perfusion-Guided Resuscitation in Vasodilatory Shock: A Systematic Review and Dual Frequentist-Bayesian Meta-Analysis of Randomized Trials.
Critical care medicine·September 11, 2026·PMID 42725818
Why it mattersPeripheral perfusion-guided resuscitation is a simple, noninvasive bedside strategy that may improve outcomes in septic shock, a condition with persistently high mortality. The high Bayesian probability of benefit, despite a nonsignificant frequentist result, suggests a potential mortality reduction that warrants attention from clinicians managing vasodilatory shock.
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