Meta-Analysishigh evidence
Platelet-Rich Plasma Is More Effective Than Hyaluronic Acid Injections for Osteoarthritis of the Knee: A Meta-analysis Based on Randomized, Double-Blinded, Controlled Clinical Trials.
Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association·December 1, 2025·PMID 40681006
Why it mattersPRP is widely used but evidence comparing it to HA has been mixed. This meta-analysis provides pooled, high-level evidence that PRP offers superior pain relief and functional improvement at 12 months, which can guide shared decision-making and treatment selection in knee OA.
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