Cohort Studymoderate evidence
Duration of Medication Use for Opioid Use Disorder and Risk of Postpartum Overdose and Death.
JAMA network open·October 1, 2026·PMID 42826020
Why it mattersOverdose is the leading cause of maternal mortality in the US, yet evidence on how MOUD duration affects postpartum risk is limited. This study provides real-world data linking continuous MOUD treatment during pregnancy and early postpartum to reduced overdose or death in the first year after delivery, informing clinical decisions about treatment duration and retention.
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