Cohort Studymoderate evidence
Integrated immune and endothelial profiling predicts 90-day mortality in postoperative sepsis and septic shock.
EBioMedicine·July 11, 2026·PMID 42435583
Why it mattersEarly risk stratification in postoperative sepsis is limited by lack of reliable biomarkers. This study identifies specific circulating immune and endothelial cell phenotypes that strongly predict 90-day mortality, offering a potential tool to guide early therapeutic decisions and monitor immune-endothelial homeostasis in critically ill surgical patients.
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