Randomized Trialhigh evidence
Comparison of Early Bracing Versus Splinting for the Initial Treatment of Acute Humeral Shaft Fractures (The COBRAS Trial).
Journal of orthopaedic trauma·August 1, 2026·PMID 42466769
Why it mattersOrthopedic surgeons managing humeral shaft fractures must balance early mobilization against patient comfort and soft-tissue complications. This trial provides Level I evidence that initial coaptation splinting reduces early pain and skin damage compared to immediate functional bracing, supporting the traditional staged approach.
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