Studymoderate evidence
Histone modification clocks for robust cross-species biological age prediction and elucidating senescence regulation.
Proceedings of the National Academy of Sciences of the United States of America·March 17, 2026·PMID 41805570
Why it mattersHistone modification clocks offer a new, robust tool for measuring biological age that may complement or surpass DNA methylation clocks, especially in species without DNA methylation. For pain medicine specialists, this could eventually inform understanding of age-related pain conditions and treatment responses.
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