Randomized Trialhigh evidence

Clinical study of a micro-implantable pulse generator for the treatment of peripheral neuropathic pain: 12-month results from the COMFORT-randomized controlled trial.

Regional anesthesia and pain medicine·March 5, 2026·PMID 39572166

Why it matters

This study provides high-level randomized evidence supporting the durability of peripheral nerve stimulation with a micro-IPG, addressing a gap in controlled data for this established therapy. It reinforces the role of neuromodulation in managing refractory neuropathic pain.

Infographic summary of Clinical study of a micro-implantable pulse generator for the treatment of peripheral neuropathic pain: 12-month results from the COMFORT-randomized controlled trial.
Visual abstract · MedLit

The papers that matter, first.

MedLit ranks the medical literature into a specialty feed with concise summaries, evidence-aware triage, and visual takeaways.

§

MedLit · Evidence, Distilled