Meta-Analysishigh evidence
Reconstruction After an Anterior Cruciate Ligament Injury Does Not Reduce the Osteoarthritis Risk But Lowers the Total Knee Arthroplasty Rate: A Systematic Review and Meta-analysis.
Orthopaedic journal of sports medicine·July 1, 2026·PMID 42539917
Why it mattersOrthopedic surgeons and sports medicine clinicians managing ACL injuries need to counsel patients on long-term joint health. This meta-analysis clarifies that while ACL reconstruction restores stability, it does not prevent radiographic osteoarthritis, yet it substantially reduces the risk of eventual knee replacement.
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