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Systems Age: a single blood methylation test to quantify aging heterogeneity across 11 physiological systems.
Nature aging·September 1, 2025·PMID 40954326
Why it mattersCurrent epigenetic clocks give a single age estimate, masking organ-specific aging differences. This tool quantifies aging across 11 systems from one blood test, potentially allowing pain specialists to identify accelerated aging in systems relevant to pain (e.g., musculoskeletal, inflammatory) and tailor interventions or monitoring.
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