Randomized Trialvery high evidence

Long-term weight loss effects of semaglutide in obesity without diabetes in the SELECT trial.

Nature medicine·July 1, 2024·PMID 38740993

Why it matters

This analysis provides the longest-term evidence to date on semaglutide's weight loss durability and safety in a high-cardiovascular-risk population without diabetes, supporting its role in chronic weight management and potentially informing cardiovascular risk reduction strategies.

Infographic summary of Long-term weight loss effects of semaglutide in obesity without diabetes in the SELECT trial.
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