Cohort Studyhigh evidence
Disparities in Cancer Incidence by Sex and Associated Lifestyle Factors and Health Conditions.
JAMA oncology·September 24, 2026·PMID 42783354
Why it mattersCancer incidence is consistently higher in males, but the extent to which this is modifiable varies by population. Understanding which risk factors drive the sex gap can inform targeted prevention strategies, especially in settings where behavioral and metabolic risks are highly prevalent.

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