Cohort Studymoderate evidence
Trajectories of oxygenation index and PEEP levels associated with 28-day mortality in sepsis-associated ARDS: a multicenter cohort study.
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases·July 2, 2026·PMID 42392525
Why it mattersDynamic oxygenation trajectories provide a simple bedside tool to identify distinct ARDS subphenotypes with markedly different prognoses. This may help emergency physicians and intensivists refine early risk stratification and consider individualized PEEP strategies rather than a one-size-fits-all approach.
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