Randomized Trialhigh evidence
Radiotherapy versus observation following surgical resection of WHO grade 2 atypical meningioma (ROAM/EORTC-1308): an international, multicentre, open-label, phase 3, randomised controlled trial.
Lancet (London, England)·September 25, 2026·PMID 42790456
Why it mattersAtypical meningioma has a high recurrence risk even after gross total resection, and the role of adjuvant radiotherapy has been uncertain. This trial provides randomized evidence that radiotherapy reduces recurrence, informing shared decision-making for patients and clinicians.
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