Guidelinehigh evidence
Pharmacologic Treatments With Lifestyle Modifications in Nonpregnant Adults With Overweight or Obesity in Outpatient Settings: A Living Clinical Guideline From the American College of Physicians (April 2026).
Annals of internal medicine·June 16, 2026·PMID 42296496
Why it mattersThis guideline provides a clear, evidence-based hierarchy of pharmacologic options for weight management, helping clinicians navigate the expanding landscape of anti-obesity medications and prioritize agents with the strongest evidence for efficacy and safety.

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