Guidelinehigh evidence

Pharmacologic Treatments With Lifestyle Modifications in Nonpregnant Adults With Overweight or Obesity in Outpatient Settings: A Living Clinical Guideline From the American College of Physicians (April 2026).

Annals of internal medicine·June 16, 2026·PMID 42296496

Why it matters

This guideline provides a clear, evidence-based hierarchy of pharmacologic options for weight management, helping clinicians navigate the expanding landscape of anti-obesity medications and prioritize agents with the strongest evidence for efficacy and safety.

Infographic summary of Pharmacologic Treatments With Lifestyle Modifications in Nonpregnant Adults With Overweight or Obesity in Outpatient Settings: A Living Clinical Guideline From the American College of Physicians (April 2026).
Visual abstract · MedLit

The papers that matter, first.

MedLit ranks the medical literature into a specialty feed with concise summaries, evidence-aware triage, and visual takeaways.

§

MedLit · Evidence, Distilled