Randomized Trialhigh evidence
Cryostick pre-cooling reduces pain during intra-articular knee injections: a randomized, contralateral-controlled trial.
The Knee·July 9, 2026·PMID 42424755
Why it mattersProcedural pain and needle phobia are common barriers to intra-articular knee injections in osteoarthritis care. This simple, non-pharmacological cooling technique offers a rapid, low-cost method to improve patient comfort and satisfaction, potentially increasing adherence to injection therapy.
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