Studyuncertain evidence
Intra-Arterial Alteplase After Successful Thrombectomy for Acute Ischemic Stroke.
JAMA·August 20, 2026·PMID 42623045
Why it mattersResidual distal occlusions and microvascular thrombosis after successful thrombectomy may limit functional recovery. If intra-arterial alteplase improves outcomes without excess bleeding, it could refine post-thrombectomy management for stroke neurologists and emergency physicians.

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