Randomized Trialhigh evidence
Cold and Room-Temperature Platelets in Cardiac Surgery: The CHIPS Randomized Clinical Trial.
JAMA·August 17, 2026·PMID 42606886
Why it mattersPlatelet shortages and wastage due to the 5-7 day shelf life of room-temperature platelets limit availability, especially in remote or low-volume centers. Cold storage up to 21 days could expand platelet inventories and reduce waste without compromising hemostasis in cardiac surgery.

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