Randomized Trialhigh evidence
Beneficial effects of the rapid vs. standard procedure for injection naltrexone initiation operate through increased adjunctive medication use.
Drug and alcohol dependence·July 1, 2026·PMID 42090840
Why it mattersIt clarifies a mechanism behind rapid naltrexone induction, highlighting that aggressive symptom management with clonidine and benzodiazepines is a key driver of success, not just the speed of the protocol.
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