Randomized Trialhigh evidence

Low-Use vs. High-Use Physical Restraint in Older Adults With Sepsis Receiving Mechanical Ventilation: A Multicenter Randomized Clinical Trial.

Journal of the American Geriatrics Society·October 27, 2026·PMID 42944623

Why it matters

Physical restraint use in mechanically ventilated older patients is common but lacks strong evidence. This trial suggests that minimizing restraints may improve short-term recovery without increasing harm, supporting restraint-reduction protocols in ICUs.

Infographic summary of Low-Use vs. High-Use Physical Restraint in Older Adults With Sepsis Receiving Mechanical Ventilation: A Multicenter Randomized Clinical Trial.
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