Cohort Studyhigh evidence

Biological aging increases risk of postoperative morbidity and mortality: an international, multi-cohort study.

npj aging·July 4, 2026·PMID 42401606

Why it matters

Biological age may capture physiological reserve and resilience beyond chronological age, offering a more personalized risk assessment for surgical patients. This could improve preoperative counseling, patient selection, and targeted prehabilitation, especially for older or seemingly fit patients undergoing complex procedures.

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