Randomized Trialhigh evidence

A novel fasting mimetic (Mimio) creates fasting-like benefits to hunger control, oxidative stress, and cardiometabolic health in humans.

Scientific reports·February 20, 2026·PMID 41720867

Why it matters

This is the first human trial to show that a daily supplement can mimic fasting-like metabolic benefits without actual caloric restriction, offering a potential adjunct for patients struggling with traditional fasting or lifestyle changes.

Infographic summary of A novel fasting mimetic (Mimio) creates fasting-like benefits to hunger control, oxidative stress, and cardiometabolic health in humans.
Visual abstract · MedLit

The papers that matter, first.

MedLit ranks the medical literature into a specialty feed with concise summaries, evidence-aware triage, and visual takeaways.

§

MedLit · Evidence, Distilled