Randomized Trialhigh evidence
Optimizing brain functional-structural architecture with cTBS to reduce relapse in alcohol use disorder: a randomized controlled trial.
Molecular psychiatry·July 15, 2026·PMID 42457860
Why it mattersRelapse in alcohol use disorder remains a major clinical challenge, and current treatments have limited efficacy. This study provides mechanistic evidence that a noninvasive brain stimulation protocol can durably reduce relapse risk by modulating prefrontal control over subcortical circuits, offering a potential network-targeted intervention for addiction medicine.
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