Randomized Trialhigh evidence
Mechanical Thrombectomy Versus Medical Management for Large Ischemic Core Stroke Identified before Inter-Hospital Transfer: A Post Hoc Analysis of the LASTE Trial.
Annals of neurology·September 22, 2026·PMID 42770646
Why it mattersPatients with large ischemic core strokes are often excluded from thrombectomy trials, yet this analysis suggests benefit even in those with ASPECTS 0-2 when transferred early. For neurologists and emergency physicians, this supports considering inter-hospital transfer for thrombectomy in this high-risk group, potentially expanding treatment eligibility.
The papers that matter, first.
MedLit ranks the medical literature into a specialty feed with concise summaries, evidence-aware triage, and visual takeaways.
§
MedLit · Evidence, Distilled