Timing of Mechanical Circulatory Support and In-Hospital Mortality in Patients With Cardiogenic Shock.

Mayo Clinic proceedings·July 21, 2026·PMID 42484571

Why it matters

Timing of MCS initiation in cardiogenic shock is a critical decision point with limited evidence. This large analysis suggests that even a one-day delay is associated with higher mortality, reinforcing the importance of early recognition and prompt escalation of support.