Randomized Trialhigh evidence
Sprint interval exercise disrupts mitochondrial ultrastructure driving a unique mitochondrial stress response and remodelling in men.
Nature communications·December 1, 2025·PMID 41326383
Why it mattersExercise intensity differentially regulates mitochondrial adaptations, with sprint-interval training triggering a stress-induced remodeling program distinct from the mitochondrial biogenesis seen with moderate-intensity continuous training. Understanding these pathways can guide exercise prescription for optimizing mitochondrial health and performance.
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