Meta-Analysislow evidence
Effects of neurokinin receptor antagonists on sleep disturbance in menopausal women: a systematic review and meta-analysis of randomized controlled trials.
Menopause (New York, N.Y.)·October 6, 2026·PMID 42837121
Why it mattersSleep disturbance is a common, burdensome symptom in menopausal women with vasomotor symptoms, and nonhormonal options are needed. This meta-analysis quantifies the benefit of NK antagonists on sleep, supporting their role for women who cannot or prefer not to use hormone therapy.

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