Randomized Trialhigh evidence
Patient-Centered Prescription Opioid Tapering Methods : A Randomized Clinical Trial.
Annals of internal medicine·July 7, 2026·PMID 42407075
Why it mattersClinicians managing patients on long-term opioids need evidence-based tapering strategies. This trial suggests that a structured, patient-centered taper alone can achieve meaningful dose reduction without worsening pain, and that adding CBT may reduce withdrawal-related adverse effects, informing shared decision-making and resource allocation.
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