Randomized Trialhigh evidence

Treatment of androgenetic alopecia in transgender people receiving testosterone therapy with sublingual minoxidil: A randomized, double-blind, placebo-controlled clinical trial.

Journal of the American Academy of Dermatology·May 14, 2026·PMID 42140362

Why it matters

Transgender patients on testosterone often develop androgenetic alopecia, yet standard treatments like 5α-reductase inhibitors may interfere with masculinization. Sublingual minoxidil offers a safe, effective alternative that does not alter testosterone concentrations, addressing a key clinical concern in this population.

Infographic summary of Treatment of androgenetic alopecia in transgender people receiving testosterone therapy with sublingual minoxidil: A randomized, double-blind, placebo-controlled clinical trial.
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