Randomized Trialhigh evidence
Fasting-induced glucose intolerance is not impacted by the addition of daily exercise: A randomized crossover study.
The Journal of physiology·July 5, 2026·PMID 42402811
Why it mattersFor clinicians advising patients on fasting protocols, this study clarifies that exercise does not counteract the acute insulin resistance induced by short-term fasting. It highlights a potential sex difference in metabolic response, which may inform personalized guidance on fasting and refeeding.

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