Randomized Trialhigh evidence

Fasting-induced glucose intolerance is not impacted by the addition of daily exercise: A randomized crossover study.

The Journal of physiology·July 5, 2026·PMID 42402811

Why it matters

For clinicians advising patients on fasting protocols, this study clarifies that exercise does not counteract the acute insulin resistance induced by short-term fasting. It highlights a potential sex difference in metabolic response, which may inform personalized guidance on fasting and refeeding.

Infographic summary of Fasting-induced glucose intolerance is not impacted by the addition of daily exercise: A randomized crossover study.
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