Randomized Trialhigh evidence
Rivaroxaban Then Aspirin vs. Aspirin Alone after Total Hip or Knee Arthroplasty.
The New England journal of medicine·July 12, 2026·PMID 42437501
Why it mattersOrthopedic surgeons seek effective, simple thromboprophylaxis after joint replacement. This trial provides high-level evidence that aspirin alone is noninferior to a short course of rivaroxaban followed by aspirin, potentially simplifying postoperative regimens and reducing costs without compromising safety.
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