Cohort Studyhigh evidence
Risk of deep vein thrombosis and pulmonary embolism after simultaneous bilateral knee arthroplasty: A Japanese nationwide medical claims database study.
Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association·November 4, 2026·PMID 42982668
Why it mattersOrthopedic surgeons and internists managing perioperative care need to weigh the convenience and cost benefits of simultaneous bilateral knee arthroplasty against a substantially increased thromboembolic risk, even with routine antithrombotic prophylaxis.

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