Randomized Trialhigh evidence
Mechanical Thrombectomy in Ischemic Stroke With a Medium or Distal Arterial Occlusion: The DISCOUNT Randomized Clinical Trial.
JAMA·July 22, 2026·PMID 42485024
Why it mattersMedium and distal vessel occlusions account for a substantial proportion of acute ischemic strokes, yet evidence for thrombectomy in this population has been limited. This trial provides high-quality data that thrombectomy does not improve functional outcomes and increases hemorrhagic complications, directly informing treatment decisions for these patients.
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