Meta-Analysishigh evidence

Weight loss and blood pressure lowering with GLP-1 receptor agonists and multi-hormone receptor modulators in overweight and obesity: a systematic review and meta-regression of phase 3 clinical trials.

EClinicalMedicine·November 1, 2026·PMID 42903654

Why it matters

Obesity-related hypertension is common, and weight loss is a cornerstone of BP management. This analysis quantifies the relationship between pharmacologically induced weight loss and BP reduction, supporting these agents as adjunctive therapy for BP control in patients with overweight or obesity.

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