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Genetic architecture of sleep in a genome wide association study of device measured sleep traits.

Nature communications·April 1, 2026·PMID 41922918

Why it matters

It provides the first genetic loci for device-measured REM and NREM sleep, highlighting sex-specific and sleep-stage-specific regulators. This advances understanding of sleep architecture biology and identifies potential therapeutic targets for sleep disorders and associated cardiometabolic disease.

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