Randomized Trialhigh evidence
Closed-Loop Insulin Delivery in Type 1 Diabetes in Pregnancy: The CIRCUIT Randomized Clinical Trial.
JAMA·December 23, 2025·PMID 41134589
Why it mattersPregnancy in type 1 diabetes requires tight glycemic control, and hyperglycemia is linked to substantial maternal-fetal risk. This trial provides high-level evidence that closed-loop insulin delivery can meaningfully improve glucose control during pregnancy compared with current standard approaches.
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