Cohort Studymoderate evidence
Prospective Evaluation of an Intraoperative Synovial Calprotectin Point-of-Care Lateral Flow Test for Periprosthetic Joint Infection in Hip and Knee Revisions.
The Journal of arthroplasty·October 27, 2026·PMID 42946101
Why it mattersRapid intraoperative diagnosis of periprosthetic joint infection remains challenging, often relying on frozen sections or delayed cultures. A point-of-care calprotectin test with high negative predictive value could help surgeons decide between one- and two-stage revisions in real time, potentially reducing unnecessary staged procedures.
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