Randomized Trialhigh evidence
Multidomain lifestyle intervention for the prevention of cognitive decline in at-risk older adults in Latin America (LatAm-FINGERS): a single-blind, multicentre, randomised controlled trial.
Lancet (London, England)·July 13, 2026·PMID 42442374
Why it mattersLatin America faces a high and growing dementia burden, yet its populations are underrepresented in prevention trials. This study demonstrates that a structured, culturally adapted lifestyle intervention is feasible and can improve cognitive trajectories in at-risk older adults, extending evidence for multidomain strategies to low- and middle-income settings.
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