Randomized Trialhigh evidence
Surgery and tile-based radiation therapy versus surgery and stereotactic radiation for newly diagnosed brain metastases (ROADS): a randomized, open-label, phase 3 trial.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology·September 28, 2026·PMID 42804720
Why it mattersPost-operative stereotactic radiation is standard after resection of brain metastases, but delays and logistical burdens can compromise outcomes. Immediate tile-based radiation offers a practical alternative that may improve local control without added toxicity.

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